• Today, strong evidence demonstrate that the hair bulge forms a reservoir of epidermal stem cells. The dermal papilla not only regulates hair follicle development and growth; it is also thought to be a reservoir of multi-stem cell lineages.
  • New research from the University of Calgary may hold the key to restoring hair growth. The findings identity the existence of a skin stem cell in adult hair follicles that may one day be targeted to stimulate new hair growth after injury, burns, disease, or ageing. …
  • Dermal stem cells induce hair follicle formation and hair growth in mice, which in turn raises their therapeutic potential to treat hair loss (alopecia) in humans.

Stem Cell Discovery Could Lead To Hair Loss Treatments

New research from the University of Calgary may hold the key to restoring hair growth. The findings identity the existence of a skin stem cell in adult hair follicles that may one day be targeted to stimulate new hair growth after injury, burns, disease, or ageing. … Hair follicles undergo a constant cycle of regeneration and degeneration. … A small number of dermal sheath cells could self-renew, giving rise to hundreds of new cells in each hair follicle.
In 2009, a University of Toronto-based research team discovered a role for dermal stem cells in the dermal papilla (base of the hair follicle). Dermal stem cells induce hair follicle formation and hair growth in mice, which in turn raises their therapeutic potential to treat hair loss (alopecia) in humans.